Skin pigmentation
research & testing plateform 

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Screening solutions for pigmentation research

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iPSC-derived melanocytes display all the key functional characteristics of normal human melanocytes, including melanin synthesis, while having, unlike the cell line, a normal karyotype. Due to their high genomic stability, their availability in unlimited quantities and their high level of inter-batch reproducibility, iPSC-derived cells are therefore the most robust and relevant tool for the execution of your screening campaigns

In order to open new horizons for scientific research in the field of pigmentation and more specifically for the testing and screening of active pharmaceutical ingredients, Phenocell offer a new & exclusive human melanocyte model derived from induced pluripotent stem cells (iPSC). 

Identify new pharmaceutical active ingredients with our selection of innovative high-throughput tests on iPSC-derived melanocytes!  

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Take advantage of the characteristics of a primoculture with the benefits of a cell line using iPSC-derived cells: 

  • high genomic stability

  • available in unlimited quantities 

  • high batch-to-batch reproducibility

iPSC-derived cells are the most relevant model for HTS studies on human cells!

Your iPSC-derived melanocyte screening campaign 

Starting from
4500€/96wp

High-throughput screening services for
pigmentation research & testing

An in vitro melanocyte model
with the characteristics of primoculture
and the advantages of cell line

Biodiversity

Phenocell's pigmentation model is based on the use of iPCS-derived melanocytes from multiple donors:

  • Human iPSC-melanocytes differentiated from asian donors

  • Human iPSC- differentiated from african donors
  • Human iPSC-melanocytes differentiated from caucasian donors

  • Human iPSC-melanocytes differentiated from albino donors

Useful for ethnic specific claim validation

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Cell culture format

Phenocell's iPCS-derived melanocytes model is available:

  • in monolayers (from 6 wp down to 96 wp)

Cell characterization

Phenocell's iPCS-derived melanocyte model is fully characterized:

  • Normal kariotype

  • High level of purity

  • Expression of key melanocyte markers
    (e.g. PAX3, MITF, PMEL17, TRYP1)

  • Melanin synthesis

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Cell functionality

Phenocell's iPSC-derived melanocyte  model is useful and validate for testing:

  • Cell toxicity & cell survival

  • Oxydative stress

  • Melanongenesis related markers (e.g. Pmel17, TYR, TRYP1, MITF)

  • Melanin synthesis (pro and anti-pigmentating effect) 

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Get a sample report on
iPSC-derived melanocyte model

Thanks! Check your box mails.

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Melanocyte related High-Throughput assays 

Find bellow some example ofpigmentation related bioassays that Phenocell offer as service :

If you do not find your favorite bioassays, do not worry,

Custom biological tests are available.

Contact us for more information.

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Management of your R&d project

Preliminary study
NDA
Project framework
Feasibility study
Quotation
Service agreement, order

Experiment
Compound receipt
iPSC culture
Testing & Bioassays

Data management
Quality control
Data analysis
Data minding

Report

Report writing
Report meeting

 

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A project? A request?
We are here to support your R&D.
Contact us to discuss.

Thanks for your message, we will contact you soon.

Vidéoconférence

Some related products
if you prefer to perform the assays in your lab!