research & testing plateform
Screening solutions for pigmentation research
iPSC-derived melanocytes display all the key functional characteristics of normal human melanocytes, including melanin synthesis, while having, unlike the cell line, a normal karyotype. Due to their high genomic stability, their availability in unlimited quantities and their high level of inter-batch reproducibility, iPSC-derived cells are therefore the most robust and relevant tool for the execution of your screening campaigns.
In order to open new horizons for scientific research in the field of pigmentation and more specifically for the testing and screening of active pharmaceutical ingredients, Phenocell offer a new & exclusive human melanocyte model derived from induced pluripotent stem cells (iPSC).
Identify new pharmaceutical active ingredients with our selection of innovative high-throughput tests on iPSC-derived melanocytes!
Take advantage of the characteristics of a primoculture with the benefits of a cell line using iPSC-derived cells:
high genomic stability
available in unlimited quantities
high batch-to-batch reproducibility
iPSC-derived cells are the most relevant model for HTS studies on human cells!
Your iPSC-derived melanocyte screening campaign
High-throughput screening services for
pigmentation research & testing
An in vitro melanocyte model
with the characteristics of primoculture
and the advantages of cell line
Phenocell's pigmentation model is based on the use of iPCS-derived melanocytes from multiple donors:
Human iPSC-melanocytes differentiated from asian donors
- Human iPSC- differentiated from african donors
Human iPSC-melanocytes differentiated from caucasian donors
Human iPSC-melanocytes differentiated from albino donors
Useful for ethnic specific claim validation
Cell culture format
Phenocell's iPCS-derived melanocytes model is available:
in monolayers (from 6 wp down to 96 wp)
Phenocell's iPCS-derived melanocyte model is fully characterized:
High level of purity
Expression of key melanocyte markers
(e.g. PAX3, MITF, PMEL17, TRYP1)
Phenocell's iPSC-derived melanocyte model is useful and validate for testing:
Cell toxicity & cell survival
Melanongenesis related markers (e.g. Pmel17, TYR, TRYP1, MITF)
Melanin synthesis (pro and anti-pigmentating effect)
Get a sample report on
iPSC-derived melanocyte model
Melanocyte related High-Throughput assays
Find bellow some example ofpigmentation related bioassays that Phenocell offer as service :
If you do not find your favorite bioassays, do not worry,
Custom biological tests are available.
Contact us for more information.
Management of your R&d project
Service agreement, order
Testing & Bioassays